Amylyx The Director, Regional Access at Amylyx will build and lead a regional access team to support patient access to a new FDA-approved therapy. This role involves developing launch readiness plans and collaborating with cross-functional partners.
Responsibilities
The Director, Regional Access will be responsible for building, launching, and leading a high-performing Regional Access organization that supports timely and appropriate patient access to a potentially newly FDA-approved, self-injectable therapy for a rare endocrine disease. This leader will develop launch readiness plans, hire and coach the regional access team, establish operating standards, and serve as a critical connector, working with Payer National Accounts, Patient Services, Specialty Pharmacy, Sales, Commercial Operations, Training, Compliance, and other cross-functional partners.
Launch Readiness and Strategy
Build and execute the regional access launch readiness plan for a rare disease endocrinology therapy with a pharmacy benefit and specialty pharmacy distribution model.
Define compliant launch regional access activities, including account readiness planning, approved disease-state education, education on approved patient-support resources where appropriate, and transition planning from launch preparation to post-approval execution.
Partner with Payer National Accounts, Trade, Patient Services, Brand, Sales, Medical, Legal, Compliance, Training, and Commercial Operations to ensure launch execution is aligned across functions.
Recruit, onboard, coach, and develop a Regional Access team responsible for regional execution of patient, provider, and payer access support.
Establish clear roles, responsibilities, performance expectations, KPIs, and management processes for the regional access organization.
Conduct regional rides, coaching sessions, business reviews, and performance assessments to drive consistent execution and continuous improvement.
Create a culture grounded in authenticity, accountability, audacity, curiosity, and engagement, while reinforcing compliance, collaboration, urgency, and patient-centered problem solving.
Qualification
10+ years of pharmaceuticalProven experience buildingDemonstrated ability to recruitStrong knowledge of regional payersAbility to translate complex payerStrong executive presenceWork Location and ConditionsAt Amylyx
Required
10+ years of pharmaceutical, biotech, market access, patient services, reimbursement, specialty pharmacy, or related commercial experience, including regional leadership.
Proven experience building, launching, scaling, and leading regional access, reimbursement, patient access, or market access teams in a complex specialty or rare disease environment.
Demonstrated ability to recruit, onboard, coach, and develop high-performing regional teams while establishing clear expectations, operating rhythms, KPIs, and accountability measures.
Experience leading teams through product launch readiness, including building deployment plans, access playbooks, training plans, and cross-functional launch execution processes.
Deep knowledge of pharmacy benefit access, specialty pharmacy, prior authorization, step therapy, denials and appeals, payer policy, HUB services, and HCP workflows.
Strong knowledge of regional payers, state Medicaid, IDN and health-system access pathways, institutional formulary processes, EMR workflows, and specialty pharmacy distribution models.
Track record of partnering effectively across Market Access, Sales, Patient Services, Specialty Pharmacy, Trade, Commercial Operations, Medical, Legal, Compliance, Training, and Analytics.
Ability to translate complex payer, provider, specialty pharmacy, and patient journey insights into compliant regional strategies, operational improvements, and scalable national solutions.
Strong executive presence, communication skills, business acumen, and ability to influence without authority across senior leaders, cross-functional partners, and regional teams
Work Location and Conditions
At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.
This is a field-based leadership role requiring customer engagement and field visits, including ride-alongs. Regular travel of approximately 50% to 60%, including overnight travel by air and automobile, is required based on business needs. The successful candidate must be able to work effectively from a home office, customer sites, and other field-based locations, and be able to travel efficiently to support assigned territories and business objectives.
