The Production Chemist performs hands-on cGMP peptide manufacturing, supporting either upstream operations (synthesis and cleavage) or downstream operations (preparative HPLC purification and lyophilization). You will carry out assigned batch tasks safely, accurately, and on schedule. Note that cross-training in the other area may follow once you are established in the role. Experience in both areas is not required; strength in either one is enough.

This role reports to the Supervisor, CGMP Manufacturing. Recent graduates are encouraged to apply; training will be provided.

This role is based in Menlo Park, CA at our H&H Peptides facility.

Execute assigned manufacturing tasks per approved batch records, SOPs, and work instructions with minimal supervision, in a timely and efficient manner.

Read work orders and batch records thoroughly and understand the instructions and final product specifications before starting each task.

Upstream: perform SPPS and cleavage operations, including resin preparation, synthesizer operation, cleavage, precipitation, and crude peptide isolation.

Upstream: verify protected amino acids batch by batch against specification, including solubility and appearance, before use.

Downstream: perform prep HPLC purification, fraction pooling, concentration, lyophilization, and final packaging.

Downstream: check analytical HPLC and mass of dissolved crude peptide and identify the target peptide peak by integration and mass spectrometry to guide purification and fraction pooling.

Handle raw materials, solvents, and reagents safely; operate and clean production equipment and instruments (such as HPLCs, centrifuges, freeze dryers, stir plates, laboratory balances, mass spectrometers (optional), sonicators, vacuum ovens, and nitrogen supply) and report issues promptly.

Prepare and label chemical solutions and buffers according to standard formulas.

Perform in-process checks and escalate unexpected results right away.

Production Chemist, CGMP Manufacturing

Responsibilities

Qualification

Required

Preferred

Benefits

Company

Hims and Hers

More roles at Hims and Hers