Plan and perform solution-phase and solid-phase synthesis of peptides and protected peptide fragments, including coupling, deprotection, resin cleavage, fragment condensation, and isolation.

Design, plan, and execute hypothesis-driven experiments, including mechanistic, kinetic, and design-of-experiment (DoE) studies, to advance platform development and process understanding of peptide synthesis and isolation.

Apply relevant analytical and computational methods, such as HPLC, LC-MS, NMR, solubility studies, and impurity profiling, to advance peptide process development.

Collaborate with engineering and analytical sciences partners to develop robust, scalable processes for peptide manufacture and isolation.

Independently troubleshoot technical challenges and recommend follow-up experiments or alternative approaches.

Communicate scientific plans, progress, results, and recommendations through presentations and written updates.

Publish research in peer-reviewed journals and present at external scientific conferences and contribute to patent filings and internal scientific communications as appropriate.

Maintain awareness of relevant scientific literature, emerging technologies, and external developments in the field.

Ensure work is conducted in alignment with applicable safety, quality, compliance, and documentation expectations.

Participate in mentoring, training, and career-development activities to build independence in research design, project leadership, and scientific communication.

PhD in organic chemistry, peptide chemistry, or a closely related discipline, awarded recently or expected before the start date.

Strong practical experience and theoretical background in organic synthetic techniques, chromatographic separations, and analytical chemistry (e.g., HPLC, LC-MS, and NMR).

Postdoctoral Fellow, Peptide Process Development

Responsibilities

Company

AbbVie

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