Scientist II - Bioprocess Cell Culture Development

South San Francisco, CA, United Statesfull time

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On Site

mid

H1B: yes

AbbVie Scientist II in Bioprocess Cell Culture Development responsible for executing cell culture and bioprocess experiments to support biologics manufacturing development. The role involves troubleshooting, data analysis, and collaboration across CMC functions to optimize bioprocess parameters.

Responsibilities

Key Accountabilities/Core Job Responsibilities
Perform routine tasks such as media/buffer preparation, thawing of cryopreserved cells, cell culture passaging, aseptic sampling and banking competently and independently to support ongoing projects in cell culture lab
Take routine analytical measurements for cell growth, gas-content analysis, pH, osmolality, nutrient and metabolite measurements and HPLC analysis of monoclonal antibody titers
Utilize technical expertise and available information to troubleshoot and resolve operational hurdles when encountered and adapt protocols as necessary
Propose novel scientific experiments in mammalian cell culture
Collaborate across CMC functions to optimize bioprocess parameters for the production of difficult-to-manufacture biologics
Execute high-throughput fed batch and batch experiments and perform data analysis of the same
Able to maintain a “can-do” attitude to complete innovative projects while being flexible in work priorities based on business needs
Perform tasks with rigorous attention to detail consistently. Prioritize tasks and contribute to a highly motivated and productive team with a sense of urgency and desire to meet project timelines
Accurately document, critically analyze/interpret data and communicate the results promptly through various electronic means
Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials
Must be comfortable with physical activities of constant standing, walking, and sitting with arm stretching into biosafety cabinets for cell culture work and occasionally lifting 50Ibs.

Qualification

Experience in standard cell cultureExperience in biochemistryStrong interpersonal skills

Required

BS or equivalent education with typically 7 or more years of experience
MS or equivalent education with typically 5 or more years of experience
Experience in standard cell culture
Experience in biochemistry
Experience in molecular biology techniques
Strong interpersonal skills
Comfortable with physical activities including standing, walking, sitting with arm stretching into biosafety cabinets, and occasionally lifting 50 lbs