Principal Software Engineer, Instrument Simulations

Alewife, Cambridge, MAfull timeOn Site

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senior

$204k–$270k

H1B: no

Lila Sciences Principal Software Engineer, Instrument Simulations at Lilasciences to architect and lead development of next-generation laboratory automation simulation platform. Responsible for designing simulation environments and integration layers connecting AI experimental design with robotic systems.

Responsibilities

Lila Sciences is seeking a Principal Software Engineer, Instrument Simulations to architect and lead the development of our next-generation laboratory automation platform. In this role, you'll be responsible for designing the simulation infrastructure and integration layer that connects AI-driven experimental design with physical robotic systems, enabling closed-loop scientific discovery at unprecedented scale.
What You'll Be Building
Architect and implement high-fidelity simulation environments that model complex laboratory instrumentation, fluidics, and robotic workflows
Design robust integration patterns between heterogeneous hardware systems, ensuring reliable and safe execution of fully automated experiments
Lead the development of APIs and interfaces that enable scientists and AI agents to seamlessly interact with sophisticated automation infrastructure
Maintain and help establish best practices for hardware-software integration, system monitoring, and CI/CD in laboratory automation contexts for all newly developed systems
Mentor engineers, likely leading a small agile team

Qualification

Excellent strategic thinking skillsPh

Required

Bachelor’s or Master’s degree in Computer Science, Engineering, or a related field: Background that supports technical and leadership capabilities.
10+ years of software development experience, including 5+ years in a leadership role: Demonstrates ability to lead and manage complex projects and engineering teams.
Proven experience in architecting and directing large-scale software projects: Skilled in designing and leading the development of scalable, reliable, and maintainable systems.
Strong proficiency in programming languages such as C++, Python, or Java: Capable of setting technical standards and guiding development practices.
Strong record of implementing and advocating for engineering best practices such as code reviews, testing, and continuous integration.
Experience in leading diverse engineering teams with a focus on collaboration, innovation, and efficiency.
Excellent strategic thinking skills, with the ability to understand and align team efforts with organizational goals.
Proven ability to mentor and develop engineering talent, fostering an environment of growth and continuous learning.
Outstanding communication and interpersonal skills: Effectively engage with stakeholders at all levels, from developers to senior executives.

Preferred

Ph.D. in Computer Science, Engineering, or a related field
Experience in leading the development of laboratory automation systems or scientific instrumentation
Experience with organizational change management and fostering innovation in large technical programs.
Track record of successful project delivery in agile environments, optimizing team workflows and balancing priorities.
Published work or presentations that highlight contributions to the field of software engineering and leadership in simulation or automation systems.

Benefits

Dental
Vision
Equity/RSU
Parental Leave
Life Insurance

Company

Lila Sciences

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Source: greenhouse

Active within the past hour

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