Senior Scientist, Computational Biology

Required

• We are seeking a highly motivated scientist with a strong computational background and significant experience in biological research. As part of the Computational Biology team, you will collaborate closely with Platform teams to advance our technologies and deepen our understanding of reagent biology. Your role will involve (1) working with biologists to design and run experiments, (2) developing methods and tools for processing and interpreting molecular data, and (3) presenting findings to an interdisciplinary audience. Your curiosity and passion will fuel your discoveries, while strong connections with biologists and data/software engineers will amplify the impact of your work.
• This is a hybrid role based in Somerville, MA, with an expectation of working onsite 2–3 days per week. We are considering candidates who are local to the Boston area or able to meet this onsite expectation.
• Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to scientific excellence.
• Meet your Manager:
• All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening.
• Andrea Calabria, Senior Director, Data Sciences
• Andrea holds a B.Sc. and M.Sc. in Engineering from the Polytechnic University of Milan, Italy, and a Ph.D. in Computer Science from the University of Milan-Bicocca, with a focus on computational biology. He has more than 15 years of experience in gene therapy, computational genomics, and genomic safety. Before joining Tessera, Andrea worked at the San Raffaele Telethon Institute for Gene Therapy in Milan, where he led molecular follow-up analyses for patients enrolled in clinical gene therapy studies. His work focused on viral vector safety, insertional mutagenesis, and human hematopoietic stem cell dynamics in vivo. Andrea joined Tessera in 2023 and leads the Computational Biology team. His group supports drug candidate programs through genotoxicity risk assessment, develops computational approaches to study gene writing biology, and builds scalable data and analysis infrastructure to support molecular assay design and knowledge mining. Andrea has authored numerous scientific publications and has an h-index of 26. His ORCID is https://orcid.org/0000-0003-3515-3384.
• Meet your Talent Partner:
• Ben Hoogheem – Senior Director, Head of Talent Management
• As Head of Talent Management at Tessera Therapeutics, Ben leads Tessera’s talent strategy across talent acquisition, performance management, and talent mobility.
• Ben began his career as an in vivo Pharmacologist, which gave him a lasting appreciation for the rigor, creativity, and collaboration that drive scientific discovery. That foundation continues to shape how he helps build organizations designed to enable science thrive.
• Ben is focused on aligning exceptional people with bold science – creating the structure, clarity, and culture that empower teams to scale effectively and achieve meaningful impact.