Chief of Staff

San Franciscofull timeRemote

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senior

$165k–$215k

H1B: no

Probablygenetic Chief of Staff at Probably Genetic to manage venture fundraising and serve as a strategic partner to the CEO. Own high-stakes initiatives and lead cross-functional projects to improve operational efficiency and investor relations.

Responsibilities

We are at an inflection point. With a Series B on the horizon and a growing portfolio of partnerships with drug developers and patient advocacy groups, we need a Chief of Staff who can operate as a true right hand to the Founder and CEO — someone who runs toward complexity, brings structure to ambiguity, and holds the highest standards of craft and detail.
Venture fundraising & existing investor relations (20%)
Own the end-to-end venture fundraising due diligence: materials, data room, investor outreach, pipeline management, and follow-through
Serve as the primary point of coordination between the CEO and prospective and existing investors
Prepare board meeting materials, manage the board cadence, and ensure follow-ups are tracked and closed
Draft investor updates, pitch narratives, and other strategic communications with precision and clarity
CEO leverage, strategic though partnership & cross-functional execution (40%)
Reduce CEO time on operational overhead by 30%+ by owning recurring processes, decision tracking, and stakeholder communication
Lead cross-functional projects that span multiple teams, ensuring clarity of ownership, timelines, and outcomes
Identify bottlenecks across the organization and build scalable processes to address them before they become problems
Prepare the CEO for key meetings with background briefs, talking points, and follow-up documentation
Strategic external communications (40%)

Qualification

8+ years of experienceProvenA collaborative

Required

We are looking for a few specific things that will help you succeed in this role:
8+ years of experience, with a strong foundation in management consulting (McKinsey, BCG, Bain, or equivalent) and subsequent operating experience at a high-growth startup
Prior experience supporting or managing a fundraising process (Series A>D ideally); demonstrated understanding of investor relations and venture dynamics
Track record of operating at the intersection of strategy and execution — you are as comfortable in a boardroom as you are building a process from scratch
Experience in healthtech or biotech or track record of operating in highly complex industries
Meticulous attention to detail — you catch errors others miss and hold every output to an exceptionally high standard
Proven, demonstrable AI literacy — you actively use AI tools (beyond prompting) in your daily workflow and can lead others in doing the same
Exceptional written communication — you write with clarity, economy, and impact
Skilled at managing multiple shifting priorities without dropping the ball — you thrive in dynamic environments where the roadmap changes week to week
High emotional intelligence and leadership presence — you know when to push, when to listen, and how to build trust quickly
A collaborative, low-ego operating style — you care about outcomes, not credit
As with all new hires at Probably Genetic, you will also need to be: