Senior Laboratory Director, Oncology

Menlo Park - 1035full timeOn Site

Apply on Employer Site

senior

$247k–$268k

H1B: yes

Billiontoone Senior Laboratory Director, Oncology leads daily operations of a high-complexity oncology clinical laboratory with accountability for quality, turnaround time, capacity, cost, and regulatory compliance. This role provides technical oversight of somatic variant interpretation and oncology report sign-out from Northstar liquid biopsy assays.

Responsibilities

Lead, build, and scale the oncology laboratory organization (technologists, supervisors, and operations managers), including headcount planning, hiring, and competency management.
Own the oncology laboratory operating budget and P&L, including COGS, operating expenses, and capital equipment planning.
Drive operational performance against turnaround-time (TAT), throughput, capacity, and quality targets; implement process improvements and automation to scale.
Lead laboratory scale-up, new-assay and instrument onboarding, inspection readiness, and vendor and capital procurement.
Provide technical oversight of somatic variant interpretation and oncology report sign-out from Northstar liquid biopsy assays, ensuring accuracy and timeliness.
Troubleshoot technical issues across oncology workflows (liquid biopsy sample prep, NGS library preparation, sequencing, and data analysis).
Ensure compliance with CLIA, CAP, and NYSDOH standards; oversee Non-Conforming Events, CAPAs, and documentation of SOPs, validations, QC records, competencies, proficiency testing, and report archives.
Collaborate with bioinformatics, R&D, and medical affairs on assay development and interpretation guidelines; serve as a subject-matter expert on oncology variant interpretation (AMP/CAP/NYS guidelines).

Qualification

Doctoral degree (PhDProven leadership developingStrong analytical

Required

Doctoral degree (PhD, MD, or equivalent) in genetics, molecular biology, or a related field, with board certification (ABMGG, ABP in Molecular Genetic Pathology, or equivalent).
Valid or eligible for California Clinical Laboratory Director license (CGMB, CGMBS, MD/DO licensure) and New York State CoQ in oncology testing.
7+ years in a regulated clinical laboratory environment (CLIA/CAP/NYSDOH), with at least 4 years in molecular oncology testing including NGS.
Proven leadership developing, validating, and implementing oncology assays (e.g., somatic mutation panels, methylation), with deep knowledge of cancer genomics (tumor heterogeneity, somatic driver mutations, targeted therapies).
Experience with variant interpretation databases (COSMIC, OncoKB, ClinVar), IGV and BAM file review, and molecular tumor boards; proficiency with LIMS and oncology bioinformatics tools.
Strong analytical, communication, and organizational skills, with a track record of leading teams in high-growth environments.

Benefits

Dental
Vision
401(k)
PTO
Equity/RSU
Annual Bonus
Parental Leave

Company

Billiontoone

View company page

Source: greenhouse

Active within the past hour

More roles at Billiontoone

Research Associate Intern

Menlo Park - 1035

Prenatal Regional Sales Manager, Denver (CO)

Remote (US)

Senior IT Desktop Support Technician

Menlo Park - 1035

Clinical Laboratory Scientist, Oncology (PM Shift)

Menlo Park - 1035

Boost Your Interview Chances

Improve Resume Match Score

Free

Your Score

9.0

Strong Applicant

Must-Have Skills for This Role

CLIACAPNYSDOHNGSliquid biopsysomatic variant interpretation

Optimize my Resume

Apply Faster with Autofill

Free

Save your profile once. LumiJobs pre-fills the employer's application form so you stop re-typing the same answers on every site.

Apply With Autofill

Or skip LumiJobs's tools and submit directly on the employer's career site.

Apply on Employer Site